ChemKovil | Chemical Industry

Our research facilities include all necessary thinks for organic synthesis, phytochemistry, nano chemistry etc. We have well equipped lab manned by highly competent and expert scientists. All analytical studies for chemkovil are out sourced from standard universities and colleges.

Basic facilities in Chemkovil

Rotary evaporator
Hot air oven
Fume hood
Chiller
Microwave oven
UV Chamber
Centrifuge
UV Laminar air flow Cabinet

Temperature controlled oil bath
Ice Maker
Preparative TLC
Open muffle furnace
High Vacuum pump
All necessary glassware
Muffle furnace (Up to 950oC)
UV-Spectrophotometer (Double beam)

Photocatalytic reactor
-20oC freezer
Orbital shaker
Double digit pH meter
Soxhlet extractor (100 mL to 5 lit)
Tissue culture Rack
Glove Box for Inert Atmosphere

Characterization studies for ChemKovil

Samples Analysis

PROJECT CODE : CK-MC-001

Synthesis of Novel DPP-4 Inhibitors (Anti-diabetic)

PROJECT CODE : CK-MC-002

Synthesis of Novel Neuraminidase Inhibitors (Swine flu)

2 Days Hands on Training on Methods of Extraction and Isolation of Chemical Constituents from Medicinal plants/Herbal plants

Objectives of the hands on training:

To understand the complexity of medicinal plant extraction and isolation of pure phytochemical constituents.

Hands on training duration: 2 days

Day - 1

Understanding the basic chemistry
Sequential solvents extraction of selected sample plants (soxhlet extraction and other methods)
Generation of crude from each extract
TLC studies of all extracts

Day - 2

Phytochemical screening of crude materials
Column chromatography studies
Characterization part of phytochemicals (NMR, FT-IR, LC-MS)

For one session of hands on training, maximum 20 peoples.
20 peoples will be separated 4 batches, each batches contain 5 peoples

Formulating the insulin to stable tablet form

Insulin is a hormone produced by body (pancreas, a gland located behind your stomach) which keeps the blood sugar level under control. It is given as an injection in type 1 and is sometimes needed in the more common form of type 2 diabetes also. Giving diabetes patients the chance to avoid the pain of needles has been the goal of our chemkovil.

Publications

Arumugam Ramachandran, Panneerselvam Anitha, Sadhasivam Gnanavel, Subramania Angaiah,Development of 1-phenyl-3-(4-(pyridin-4-ylmethyl)phenyl)urea derivatives as robust corrosion inhibitors for mild steel in 1 M HCl environment: Insight from ,molecular, experimental, and microscopic-scale modelling approaches, Journal of Environmental Chemical Engineering, Volume 12, Issue 1, 2024, 111648 [ELSEVIER Impact factor: 7.4]
Gnanavel Sadhasivam, Molecular Docking Studies of Some Natural Products Against SARS-CoV-2 Main Protease: Potential Therapeutic Agents for COVID-19, Asian J. Org. Med. Chem./ 2020 / 5(3) / pp 254-264 (UGC listed).
Vijayan Raji, Chitra Loganathan, Gnanavel Sadhasivam, Saravanan Kandasamy, Kumaradhas Poomani, Palvannan Thayumanavan, Purification of fucoxanthin from Sargassum wightii Greville and understanding the inhibition of angiotensin 1-converting enzyme: An in vitro and in silico studies, International Journal of Biological Macromolecules 148 (2020) 696–703 [ELSEVIER Impact factor: 5.16 (2020)]

Gnanavel sadhasivam, Saranya Tamilarasan, Phytochemical Screening Study on Andrographis echioides Leaves extract, Maxene Journal of Chemical Science, 2018, 2(1), 1-7

Projects